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COI Federal Regulations

The federal regulations are aimed at ensuring that the design, conduct, or reporting of research funded under grants and cooperative agreements will not be biased by any conflicting financial interest of the Investigators responsible for the research.

42CFR Part50 Subpart F - Promoting Objectivity in Research

AAG Jan 2010 chapter IV(A) - NSF Conflicts of Interest Policy

NIH Federal FAQ's


An “Investigator” is defined as the Principal Investigator and any other person who is responsible for the design, conduct, or reporting of funded research, or proposed for funding, including subgrantees, contractors, or collaborators.  The definition of Investigator includes the Investigator’s spouse and dependent children.

The term “significant financial interest” means anything of monetary value, including, but not limited to, salary or other payments for services (e.g., consulting fees or honoraria); equity interest (e.g., stocks, stock options or other ownership interests); and intellectual property rights (e.g., patents, copyrights and royalties from such rights).